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Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by SARS coronavirus and human coronavirus 229E.

Identifieur interne : 002B60 ( Main/Exploration ); précédent : 002B59; suivant : 002B61

Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by SARS coronavirus and human coronavirus 229E.

Auteurs : B S F. Tang [République populaire de Chine] ; K H Chan ; V C C. Cheng ; K Y Yuen

Source :

RBID : pubmed:20393221

Descripteurs français

English descriptors

Abstract

During the early stages of infection, SARS-CoV produces more severe perturbation of host cell gene expression in a human epithelial cell line of liver origin than the HCoV-229E.

PubMed: 20393221


Affiliations:


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<nlm:affiliation>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital Compound, Pokfulam Road, Hong Kong SAR, China. bonetang@hksh.com</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
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<name sortKey="Yuen, K Y" sort="Yuen, K Y" uniqKey="Yuen K" first="K Y" last="Yuen">K Y Yuen</name>
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<term>Gene Expression Regulation</term>
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<term>Microarray Analysis (methods)</term>
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<term>Analyse sur microréseau ()</term>
<term>Coronavirus humain 229E (métabolisme)</term>
<term>Humains</term>
<term>Infections à coronavirus (métabolisme)</term>
<term>Lignée cellulaire tumorale</term>
<term>Régulation de l'expression des gènes</term>
<term>Syndrome respiratoire aigu sévère (métabolisme)</term>
<term>Transcription génétique</term>
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